Ontology highlight
ABSTRACT:
SUBMITTER: van den Hout A
PROVIDER: S-EPMC2742499 | biostudies-literature | 2009 Oct
REPOSITORIES: biostudies-literature
van den Hout Ardo A Matthews Fiona E FE
Biostatistics (Oxford, England) 20090731 4
Interval-censored longitudinal data taken from a Norwegian study of individuals with Parkinson's disease are investigated with respect to the onset of dementia. Of interest are risk factors for dementia and the subdivision of total life expectancy (LE) into LE with and without dementia. To estimate LEs using extrapolation, a parametric continuous-time 3-state illness-death Markov model is presented in a Bayesian framework. The framework is well suited to allow for heterogeneity via random effect ...[more]