Ontology highlight
ABSTRACT:
SUBMITTER: McWilliams RR
PROVIDER: S-EPMC2742574 | biostudies-literature | 2009 Sep
REPOSITORIES: biostudies-literature
McWilliams Robert R RR Bamlet William R WR de Andrade Mariza M Rider David N DN Couch Fergus J FJ Cunningham Julie M JM Matsumoto Martha E ME Rabe Kari G KG Hammer Traci J TJ Petersen Gloria M GM
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20090818 9
<h4>Background</h4>Inherited risk of pancreatic cancer has been associated with mutations in several genes, including BRCA2, CDKN2A (p16), PRSS1, and PALB2. We hypothesized that common variants in these genes, single nucleotide polymorphisms (SNP), may also influence risk for pancreatic cancer development.<h4>Methods</h4>A clinic-based case-control study in non-Hispanic white persons compared 1,143 patients with pancreatic adenocarcinoma with 1,097 healthy controls. Twenty-eight genes directly a ...[more]