Ontology highlight
ABSTRACT:
SUBMITTER: Carlson PE
PROVIDER: S-EPMC2742718 | biostudies-literature | 2009 Sep
REPOSITORIES: biostudies-literature
Carlson Paul E PE Carr Katherine A KA Janes Brian K BK Anderson Erica C EC Hanna Philip C PC
PloS one 20090921 9
Lack of available iron is one of many environmental challenges that a bacterium encounters during infection and adaptation to iron starvation is important for the pathogen to efficiently replicate within the host. Here we define the transcriptional response of B. anthracis Sterne (34F(2)) to iron depleted conditions. Genome-wide transcript analysis showed that B. anthracis undergoes considerable changes in gene expression during growth in iron-depleted media, including the regulation of known an ...[more]