Distribution, regulation and role of the agmatine deiminase system in mutans streptococci.
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ABSTRACT:
SUBMITTER: Griswold AR
PROVIDER: S-EPMC2742967 | biostudies-literature | 2009 Feb
REPOSITORIES: biostudies-literature
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Distribution, regulation and role of the agmatine deiminase system in mutans streptococci.
Griswold A R AR Nascimento M M MM Burne R A RA
Oral microbiology and immunology 20090201 1
The agmatine deiminase system (AgDS) was identified in seven strains of mutans streptococci. Genes encoding the AgDS of Streptococcus rattus FA-1 were sequenced and found to share homology with the agu genes of Streptococcus mutans UA159. With the exception of Streptococcus sobrinus, the AgDS of mutans streptococci appear to be sensitive to carbohydrate catabolite repression. Agmatine inhibited bacterial growth, suggesting that the AgDS degrades a deleterious substance into useful compounds. ...[more]
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