Ontology highlight
ABSTRACT:
SUBMITTER: Parisien M
PROVIDER: S-EPMC2743038 | biostudies-literature | 2009 Oct
REPOSITORIES: biostudies-literature
Parisien Marc M Cruz José Almeida JA Westhof Eric E Major François F
RNA (New York, N.Y.) 20090826 10
To benchmark progress made in RNA three-dimensional modeling and assess newly developed techniques, reliable and meaningful comparison metrics and associated tools are necessary. Generally, the average root-mean-square deviations (RMSDs) are quoted. However, RMSD can be misleading since errors are spread over the whole molecule and do not account for the specificity of RNA base interactions. Here, we introduce two new metrics that are particularly suitable to RNAs: the deformation index and defo ...[more]