Ontology highlight
ABSTRACT:
SUBMITTER: Pasarica M
PROVIDER: S-EPMC2744363 | biostudies-literature | 2008
REPOSITORIES: biostudies-literature
Archives of virology 20081002 11
Human adenovirus Ad36 is causally and correlatively associated in animals and humans, respectively, with increased adiposity and altered metabolic profile. We inoculated rats with Ad36 or UV-inactivated Ad36, or mock-infected them. Four days later, Ad36-infected rats showed 23% greater epididymal fat pad weight and viral mRNA; the viral DNA could also be detected in tissues viz. the liver, brain, and adipose tissue. Intranasal or intra-peritoneal routes of viral inoculation showed similar tissue ...[more]