UFO: a web server for ultra-fast functional profiling of whole genome protein sequences.

ABSTRACT:

Background

Functional profiling is a key technique to characterize and compare the functional potential of entire genomes. The estimation of profiles according to an assignment of sequences to functional categories is a computationally expensive task because it requires the comparison of all protein sequences from a genome with a usually large database of annotated sequences or sequence families.

Description

Based on machine learning techniques for Pfam domain detection, the UFO web server for ultra-fast functional profiling allows researchers to process large protein sequence collections instantaneously. Besides the frequencies of Pfam and GO categories, the user also obtains the sequence specific assignments to Pfam domain families. In addition, a comparison with existing

SUBMITTER: Meinicke P 

PROVIDER: S-EPMC2744726 | biostudies-literature | 2009 Sep

REPOSITORIES: biostudies-literature