Ontology highlight
ABSTRACT:
SUBMITTER: Csiszar A
PROVIDER: S-EPMC2745434 | biostudies-literature | 2009 Sep
REPOSITORIES: biostudies-literature
Csiszar Anna A Labinskyy Nazar N Olson Susan S Pinto John T JT Gupte Sachin S Wu Joseph M JM Hu Furong F Ballabh Praveen P Podlutsky Andrej A Losonczy Gyorgy G de Cabo Rafael R de Cabo Rafael R Mathew Rajamma R Wolin Michael S MS Ungvari Zoltan Z
Hypertension (Dallas, Tex. : 1979) 20090713 3
Proliferation of pulmonary arterial smooth muscle cells, endothelial dysfunction, oxidative stress, and inflammation promotes the development of pulmonary hypertension. Resveratrol is a polyphenolic compound that exerts antioxidant and anti-inflammatory protective effects in the systemic circulation, but its effects on pulmonary arteries remain poorly defined. The present study was undertaken to investigate the efficacy of resveratrol to prevent pulmonary hypertension. Rats injected with monocro ...[more]