Ontology highlight
ABSTRACT:
SUBMITTER: Chinta SJ
PROVIDER: S-EPMC2745484 | biostudies-literature | 2009 Sep
REPOSITORIES: biostudies-literature
Chinta Shankar J SJ Poksay Karen S KS Kaundinya Gaayatri G Hart Matthew M Bredesen Dale E DE Andersen Julie K JK Rao Rammohan V RV
Journal of molecular neuroscience : MN 20090115 1-2
Resveratrol, a naturally occurring polyphenol, exhibits antioxidant, antiaging, and anticancer activity. Resveratrol has also been shown to inhibit tumor initiation, promotion, and progression in a variety of cell culture systems. Earlier, we showed that paraquat, a bipyridyl herbicide, triggers endoplasmic reticulum stress, cell dysfunction, and dopaminergic cell death. Due to its antioxidant activity, we assessed the ability of resveratrol to rescue cells from the toxic effects of paraquat. Wh ...[more]