Ontology highlight
ABSTRACT:
SUBMITTER: Carmichael ST
PROVIDER: S-EPMC2745827 | biostudies-literature | 2008 Nov
REPOSITORIES: biostudies-literature
Carmichael S Thomas ST Vespa Paul M PM Saver Jeffery L JL Coppola Giovanni G Geschwind Daniel H DH Starkman Sidney S Miller Chad M CM Kidwell Chelsea S CS Liebeskind David S DS Martin Neil A NA
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20080716 11
Intracerebral hemorrhage (ICH) produces a high rate of death and disability. The molecular mechanisms of damage in perihematomal tissue in humans have not been systematically characterized. This study determines the gene expression profile and molecular networks that are induced in human perihematomal tissue through molecular analysis of tissue obtained from endoscopic clot evacuation. Differentially expressed genes and their cellular origin were confirmed in a mouse model of ICH. A total of 624 ...[more]