Hsp70 structure, function, regulation and influence on yeast prions.
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ABSTRACT:
SUBMITTER: Sharma D
PROVIDER: S-EPMC2746719 | biostudies-literature | 2009
REPOSITORIES: biostudies-literature
Publications
Hsp70 structure, function, regulation and influence on yeast prions.
Sharma Deepak D Masison Daniel C DC
Protein and peptide letters 20090101 6
Heat shock proteins protect cells from various conditions of stress. Hsp70, the most ubiquitous and highly conserved Hsp, helps proteins adopt native conformation or regain function after misfolding. Various co-chaperones specify Hsp70 function and broaden its substrate range. We discuss Hsp70 structure and function, regulation by co-factors and influence on propagation of yeast prions. ...[more]
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