Ontology highlight
ABSTRACT:
SUBMITTER: Chung YK
PROVIDER: S-EPMC2747790 | biostudies-literature | 2009
REPOSITORIES: biostudies-literature
Chung Ying Kit YK Fu Gregory C GC
Angewandte Chemie (International ed. in English) 20090101 12
Chiral phosphepine 1 catalyzes the transformation of an array of hydroxy-2-alkynoates into saturated oxygen heterocycles with good enantioselectivity. Phenols are also shown to participate in such phosphine-catalyzed cyclizations, including an asymmetric variant. This method provides a new approach to the enantioselective synthesis of tetrahydrofurans, tetrahydropyrans, and dihydrobenzopyrans. ...[more]