Dipyridodiazepinone derivatives; synthesis and anti HIV-1 activity.
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ABSTRACT:
SUBMITTER: Khunnawutmanotham N
PROVIDER: S-EPMC2748688 | biostudies-literature | 2009 Jul
REPOSITORIES: biostudies-literature
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Dipyridodiazepinone derivatives; synthesis and anti HIV-1 activity.
Khunnawutmanotham Nisachon N Chimnoi Nitirat N Thitithanyanont Arunee A Saparpakorn Patchreenart P Choowongkomon Kiattawee K Pungpo Pornpan P Hannongbua Supa S Techasakul Supanna S
Beilstein journal of organic chemistry 20090722
Ten dipyridodiazepinone derivatives were synthesized and evaluated for their anti HIV-1 reverse transcriptase activity against wild-type and mutant type enzymes, K103N and Y181C. Two of them were found to be promising inhibitors for HIV-1 RT. ...[more]
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