Membrane protein crystallization in amphiphile phases: practical and theoretical considerations.
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ABSTRACT:
SUBMITTER: Nollert P
PROVIDER: S-EPMC2748814 | biostudies-literature | 2005 Jul
REPOSITORIES: biostudies-literature
Publications
Membrane protein crystallization in amphiphile phases: practical and theoretical considerations.
Progress in biophysics and molecular biology 20041007 3
Integral membrane proteins are amphiphilic molecules. In order to enable chromatographic purification and crystallization, a complementary amphiphilic microenvironment must be created and maintained. Various types of amphiphilic phases have been employed in crystallizations and intricate amphiphilic microenvironmental structures have resulted from these and are found inside membrane protein crystals. In this review the process of crystallization is put into the context of amphiphile phase transi ...[more]
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