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Control of the postmating behavioral switch in Drosophila females by internal sensory neurons.

ABSTRACT: Mating induces changes in the receptivity and egg-laying behavior in Drosophila females, primarily due to a peptide pheromone called sex peptide which is transferred with the sperm into the female reproductive tract during copulation. Whereas sex peptide is generally believed to modulate fruitless-GAL4-expressing neurons in the central nervous system to produce behavioral changes, we found that six to eight sensory neurons on the reproductive tract labeled by both ppk-GAL4 and fruitless-GAL4 can sense sex peptide to control the induction of postmating behaviors. In these sensory neurons, sex peptide appears to act through Pertussis toxin-sensitive G proteins and suppression of protein kinase A activity to reduce synaptic output. Our results uncover a neuronal mechanism by which sex peptide exerts its control over reproductive behaviors in Drosophila females.

SUBMITTER: Yang CH

PROVIDER: S-EPMC2748846 | biostudies-literature | 2009 Feb

REPOSITORIES: biostudies-literature

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Control of the postmating behavioral switch in Drosophila females by internal sensory neurons.

Yang Chung-Hui CH Rumpf Sebastian S Xiang Yang Y Gordon Michael D MD Song Wei W Jan Lily Y LY Jan Yuh-Nung YN

Neuron 20090201 4

Mating induces changes in the receptivity and egg-laying behavior in Drosophila females, primarily due to a peptide pheromone called sex peptide which is transferred with the sperm into the female reproductive tract during copulation. Whereas sex peptide is generally believed to modulate fruitless-GAL4-expressing neurons in the central nervous system to produce behavioral changes, we found that six to eight sensory neurons on the reproductive tract labeled by both ppk-GAL4 and fruitless-GAL4 can ...[more]

PMID: 19249273

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2012-01-01 | GSE27454 | GEO

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