Ontology highlight
ABSTRACT:
SUBMITTER: Bhatti P
PROVIDER: S-EPMC2750838 | biostudies-literature | 2009 Jun
REPOSITORIES: biostudies-literature
Bhatti Parveen P Stewart Patricia A PA Hutchinson Amy A Rothman Nathaniel N Linet Martha S MS Inskip Peter D PD Rajaraman Preetha P
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20090601 6
There is some evidence that oxidative stress plays a role in lead-induced toxicity. Mechanisms for dealing with oxidative stress may be of particular relevance in the brain given the high rate of oxygen metabolism. Using a hospital-based case-control study, we investigated the role of oxidative stress in the potential carcinogenicity of lead through examination of effect modification of the association between occupational lead exposure and brain tumors by single nucleotide polymorphisms in gene ...[more]