Ontology highlight
ABSTRACT:
SUBMITTER: Pandey NR
PROVIDER: S-EPMC2751572 | biostudies-literature | 2009 Oct
REPOSITORIES: biostudies-literature
Pandey Nihar R NR Renwick Joanna J Rabaa Seham S Misquith Ayesha A Kouri Lara L Twomey Erin E Sparks Daniel L DL
The American journal of pathology 20090828 4
Linoleic acid-phospholipids stimulate high-density lipoprotein (HDL) net secretion from liver cells by blocking the endocytic recycling of apoA-I. Experiments were undertaken to determine whether apoA-I accumulation in the cell media is associated with membrane ATPase expression. Treatment of HepG2 cells with dilinoeoylphosphatidylcholine (DLPC) increased apoA-I secretion fourfold. DLPC also significantly reduced cell surface F1-ATPase expression and reduced cellular ATP binding cassette (ABC)A1 ...[more]