Ontology highlight
ABSTRACT:
SUBMITTER: Koya E
PROVIDER: S-EPMC2752202 | biostudies-literature | 2009 Aug
REPOSITORIES: biostudies-literature
Koya Eisuke E Golden Sam A SA Harvey Brandon K BK Guez-Barber Danielle H DH Berkow Alexander A Simmons Danielle E DE Bossert Jennifer M JM Nair Sunila G SG Uejima Jamie L JL Marin Marcelo T MT Mitchell Timothy B TB Farquhar David D Ghosh Sukhen C SC Mattson Brandi J BJ Hope Bruce T BT
Nature neuroscience 20090720 8
Learned associations between effects of abused drugs and the drug administration environment are important in drug addiction. Histochemical and electrophysiological studies suggest that these associations are encoded in sparsely distributed nucleus accumbens neurons that are selectively activated by drugs and drug-associated cues. Although correlations have been observed between nucleus accumbens neuronal activity and responsivity to drugs and drug cues, no technique exists for selectively manip ...[more]