Ontology highlight
ABSTRACT:
SUBMITTER: Gay SC
PROVIDER: S-EPMC2756168 | biostudies-literature | 2009 Oct
REPOSITORIES: biostudies-literature
Acta crystallographica. Section D, Biological crystallography 20090916 Pt 10
The Tbd_0210 gene of the chemolithotrophic bacterium Thiobacillus denitrificans is annotated to encode a 60.5 kDa bifunctional enzyme with ATP sulfurylase and APS kinase activity. This putative bifunctional enzyme was cloned, expressed and structurally characterized. The 2.95 A resolution X-ray crystal structure reported here revealed a hexameric assembly with D(3) symmetry. Each subunit contains a large N-terminal sulfurylase-like domain and a C-terminal APS kinase domain reminiscent of the two ...[more]