Advances in autism genetics: on the threshold of a new neurobiology.
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ABSTRACT:
SUBMITTER: Abrahams BS
PROVIDER: S-EPMC2756414 | biostudies-literature | 2008 May
REPOSITORIES: biostudies-literature
Publications
Advances in autism genetics: on the threshold of a new neurobiology.
Abrahams Brett S BS Geschwind Daniel H DH
Nature reviews. Genetics 20080501 5
Autism is a heterogeneous syndrome defined by impairments in three core domains: social interaction, language and range of interests. Recent work has led to the identification of several autism susceptibility genes and an increased appreciation of the contribution of de novo and inherited copy number variation. Promising strategies are also being applied to identify common genetic risk variants. Systems biology approaches, including array-based expression profiling, are poised to provide additio ...[more]
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