Complex glycan catabolism by the human gut microbiota: the Bacteroidetes Sus-like paradigm.
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ABSTRACT:
SUBMITTER: Martens EC
PROVIDER: S-EPMC2757170 | biostudies-literature | 2009 Sep
REPOSITORIES: biostudies-literature
Publications
Complex glycan catabolism by the human gut microbiota: the Bacteroidetes Sus-like paradigm.
Martens Eric C EC Koropatkin Nicole M NM Smith Thomas J TJ Gordon Jeffrey I JI
The Journal of biological chemistry 20090624 37
Trillions of microbes inhabit the distal gut of adult humans. They have evolved to compete efficiently for nutrients, including a wide array of chemically diverse, complex glycans present in our diets, secreted by our intestinal mucosa, and displayed on the surfaces of other gut microbes. Here, we review how members of the Bacteroidetes, one of two dominant gut-associated bacterial phyla, process complex glycans using a series of similarly patterned, cell envelope-associated multiprotein systems ...[more]
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