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A specific role for posterior dorsolateral striatum in human habit learning.

ABSTRACT: Habits are characterized by an insensitivity to their consequences and, as such, can be distinguished from goal-directed actions. The neural basis of the development of demonstrably outcome-insensitive habitual actions in humans has not been previously characterized. In this experiment, we show that extensive training on a free-operant task reduces the sensitivity of participants' behavior to a reduction in outcome value. Analysis of functional magnetic resonance imaging data acquired during training revealed a significant increase in task-related cue sensitivity in a right posterior putamen-globus pallidus region as training progressed. These results provide evidence for a shift from goal-directed to habit-based control of instrumental actions in humans, and suggest that cue-driven activation in a specific region of dorsolateral posterior putamen may contribute to the habitual control of behavior in humans.

SUBMITTER: Tricomi E

PROVIDER: S-EPMC2758609 | biostudies-literature | 2009 Jun

REPOSITORIES: biostudies-literature

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A specific role for posterior dorsolateral striatum in human habit learning.

Tricomi Elizabeth E Balleine Bernard W BW O'Doherty John P JP

The European journal of neuroscience 20090521 11

Habits are characterized by an insensitivity to their consequences and, as such, can be distinguished from goal-directed actions. The neural basis of the development of demonstrably outcome-insensitive habitual actions in humans has not been previously characterized. In this experiment, we show that extensive training on a free-operant task reduces the sensitivity of participants' behavior to a reduction in outcome value. Analysis of functional magnetic resonance imaging data acquired during tra ...[more]

PMID: 19490086

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