Ontology highlight
ABSTRACT:
SUBMITTER: Nan H
PROVIDER: S-EPMC2758927 | biostudies-literature | 2009 Sep
REPOSITORIES: biostudies-literature
Nan Hongmei H Kraft Peter P Qureshi Abrar A AA Guo Qun Q Chen Constance C Hankinson Susan E SE Hu Frank B FB Thomas Gilles G Hoover Robert N RN Chanock Stephen S Hunter David J DJ Han Jiali J
The Journal of investigative dermatology 20090402 9
We conducted a multistage genome-wide association study (GWAS) of tanning response after exposure to sunlight in over 9,000 men and women of European ancestry who live in the United States. An initial analysis of 528,173 single-nucleotide polymorphisms (SNPs) genotyped on 2,287 women identified LOC401937 (rs966321) on chromosome 1 as a novel locus highly associated with tanning ability, and we confirmed this association in 870 women controls from a skin cancer case-control study with joint P-val ...[more]