Variability of DNA microarray gene expression profiles in cultured rat primary hepatocytes.
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ABSTRACT:
SUBMITTER: Xu J
PROVIDER: S-EPMC2759134 | biostudies-literature | 2007 Nov
REPOSITORIES: biostudies-literature
Publications
Variability of DNA microarray gene expression profiles in cultured rat primary hepatocytes.
Xu Jun J Deng Xutao X Chan Victor V Kelley-Loughnane Nancy N Harker Brent W BW Shi Leming L Hussain Saber M SM Frazier John M JM Wang Charles C
Gene regulation and systems biology 20071118
DNA microarray is a powerful tool in biomedical research. However, transcriptomic profiling using DNA microarray is subject to many variations including biological variability. To evaluate the different sources of variation in mRNA gene expression profiles, gene expression profiles were monitored using the Affymetrix RatTox U34 arrays in cultured primary hepatocytes derived from six rats over a 26 hour period at 6 time points (0 h, 2h, 5h, 8h, 14 h and 26 h) with two replicate arrays at each tim ...[more]
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