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Construction of a DNA nano-object directly demonstrates computation.


ABSTRACT: We demonstrate a computing method in which a DNA nano-object representing the solution of a problem emerges as a result of self-assembly. We report an experiment in which three-vertex colorability for a six-vertex graph with nine edges is solved by constructing a DNA molecule representing the colored graph itself. Our findings show that computation based on "shape processing" is a viable alternative to symbol processing when computing by molecular self-assembly.

SUBMITTER: Wu G 

PROVIDER: S-EPMC2763046 | biostudies-literature | 2009 Nov

REPOSITORIES: biostudies-literature

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Construction of a DNA nano-object directly demonstrates computation.

Wu Gang G   Jonoska Natasha N   Seeman Nadrian C NC  

Bio Systems 20090714 2


We demonstrate a computing method in which a DNA nano-object representing the solution of a problem emerges as a result of self-assembly. We report an experiment in which three-vertex colorability for a six-vertex graph with nine edges is solved by constructing a DNA molecule representing the colored graph itself. Our findings show that computation based on "shape processing" is a viable alternative to symbol processing when computing by molecular self-assembly. ...[more]

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