Droplet interface bilayers.
Ontology highlight
ABSTRACT:
SUBMITTER: Bayley H
PROVIDER: S-EPMC2763081 | biostudies-literature | 2008 Dec
REPOSITORIES: biostudies-literature
Publications
Droplet interface bilayers.
Bayley Hagan H Cronin Brid B Heron Andrew A Holden Matthew A MA Hwang William L WL Syeda Ruhma R Thompson James J Wallace Mark M
Molecular bioSystems 20080905 12
Droplet interface bilayers (DIBs) provide a superior platform for the biophysical analysis of membrane proteins. The versatile DIBs can also form networks, with features that include built-in batteries and sensors. ...[more]
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Project description:Impact statementThe paper presents a comprehensive review of integral membrane protein studies utilizing droplet interface bilayers. Droplet interface bilayers are a novel method of constructing artificial lipid bilayers with enhanced stability and physicochemical complexity compared to existing methods. Their unique morphology also suggests applications in the construction of synthetic biological systems and protocells. As well as serving as a guide to in vitro membrane protein functional studies using droplet interface bilayers in the literature to date, a novel in vitro study of a flippase protein in a droplet interface bilayer is presented.
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