Ontology highlight
ABSTRACT:
SUBMITTER: Jia L
PROVIDER: S-EPMC2765160 | biostudies-literature | 2009 Oct
REPOSITORIES: biostudies-literature
Jia Li L Oh Edwin C T EC Ng Lily L Srinivas Maya M Brooks Matthew M Swaroop Anand A Forrest Douglas D
Proceedings of the National Academy of Sciences of the United States of America 20090924 41
Rods and cones are morphologically and developmentally distinct photoreceptor types with different functions in vision. Cones mediate daylight and color vision and in most mammals express M and S opsin photopigments for sensitivity to medium-long and short light wavelengths, respectively. Rods mediate dim light vision and express rhodopsin photopigment. The transcription factor networks that direct differentiation of each photoreceptor type are incompletely defined. Here, we report that Rorb(-/- ...[more]