ETX1 is over-expressed in the glaucomatous trabecular meshwork.
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ABSTRACT:
SUBMITTER: Iragavarapu S
PROVIDER: S-EPMC2765241 | biostudies-literature | 2009 Oct
REPOSITORIES: biostudies-literature
Publications
ETX1 is over-expressed in the glaucomatous trabecular meshwork.
Iragavarapu Saradha S Algeciras Mabel E ME Lee Richard K RK Bhattacharya Sanjoy K SK
Molecular vision 20091016
<h4>Purpose</h4>To determine whether exon-trapped X chromosome clone 1 (ETX1) is overexpressed in the trabecular meshwork (TM) of glaucomatous human eyes compared to controls.<h4>Methods</h4>Immunohistochemical, western blot, and enzyme-linked immunosorbent assay analysis were used with human tissues and TM protein extracts. Reverse transcription-PCR was performed on isolated mRNA-derived cDNA preparations.<h4>Results</h4>Elevated expression levels of ETX1 were detected in glaucomatous compared ...[more]
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