Ontology highlight
ABSTRACT:
SUBMITTER: Lau NC
PROVIDER: S-EPMC2765285 | biostudies-literature | 2009 Oct
REPOSITORIES: biostudies-literature
Lau Nelson C NC Robine Nicolas N Martin Raquel R Chung Wei-Jen WJ Niki Yuzo Y Berezikov Eugene E Lai Eric C EC
Genome research 20090618 10
Piwi proteins, a subclass of Argonaute-family proteins, carry approximately 24-30-nt Piwi-interacting RNAs (piRNAs) that mediate gonadal defense against transposable elements (TEs). We analyzed the Drosophila ovary somatic sheet (OSS) cell line and found that it expresses miRNAs, endogenous small interfering RNAs (endo-siRNAs), and piRNAs in abundance. In contrast to intact gonads, which contain mixtures of germline and somatic cell types that express different Piwi-class proteins, OSS cells are ...[more]