Ontology highlight
ABSTRACT:
SUBMITTER: Godecke T
PROVIDER: S-EPMC2765500 | biostudies-literature | 2009 Mar
REPOSITORIES: biostudies-literature
Journal of natural products 20090301 3
As an extension of work on the recently discovered nitrogenous metabolites from Cimicifuga/Actaea species, three new guanidine alkaloids have been isolated and characterized from C. racemosa (syn. A. racemosa) roots. Of these, cyclo-cimipronidine (1) and cimipronidine methyl ester (2) are congeners of cimipronidine (3), whereas dopargine (5) is a derivative of dopamine. By employing NMR- and MS-guided chemodiversity profiling of a polar serotonergic (5-HT(7)) fraction, the guanidine alkaloids we ...[more]