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Structures of kinesin motor proteins.


ABSTRACT: Almost 25 years of kinesin research have led to the accumulation of a large body of knowledge about this widespread superfamily of motor and nonmotor proteins present in all eukaryotic cells. This review covers developments in kinesin research with an emphasis on structural aspects obtained by X-ray crystallography and cryoelectron microscopy 3-D analysis on kinesin motor domains complexed to microtubules.

SUBMITTER: Marx A 

PROVIDER: S-EPMC2765580 | biostudies-literature | 2009 Nov

REPOSITORIES: biostudies-literature

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Structures of kinesin motor proteins.

Marx Alexander A   Hoenger Andreas A   Mandelkow Eckhard E  

Cell motility and the cytoskeleton 20091101 11


Almost 25 years of kinesin research have led to the accumulation of a large body of knowledge about this widespread superfamily of motor and nonmotor proteins present in all eukaryotic cells. This review covers developments in kinesin research with an emphasis on structural aspects obtained by X-ray crystallography and cryoelectron microscopy 3-D analysis on kinesin motor domains complexed to microtubules. ...[more]

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