Ontology highlight
ABSTRACT:
SUBMITTER: Sinha R
PROVIDER: S-EPMC2766027 | biostudies-literature | 2009 Nov
REPOSITORIES: biostudies-literature
Sinha Ritwik R Igo Robert P RP Saini Shiv K SK Elston Robert C RC Luo Yuqun Y
Genetic epidemiology 20091101 7
Intermediate fine mapping has received considerable attention recently, with the goal of providing statistically precise and valid chromosomal regions for fine mapping following initial identification of broad regions that are linked to a disease. The following classes of methods have been proposed and compared in the literature: (1) LOD-support intervals, (2) generalized estimating equations, (3) bootstrap, and (4) confidence set inference framework. These methods provide confidence intervals e ...[more]