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Primary malignant pericardial mesothelioma - a rare cause of pericardial effusion and consecutive constrictive pericarditis: a case report.


ABSTRACT:

Introduction

Primary malignant pericardial mesothelioma is a very rare pericardial tumor of unknown etiology.

Case presentation

A 61-year-old Caucasian woman was admitted to our hospital complaining of exertional dyspnea due to a large pericardial effusion. Intrapericardial fluid volume declined after repeated pericardiocentesis, but the patient progressively developed a hemodynamically relevant pericardial constriction. Pericardiectomy revealed a pericardial mesothelioma. Subsequently, four cycles of chemotherapy (dosage according to recently published trials) were administered. The patient remained asymptomatic, and there was no recurrence of the tumor after three years.

Conclusion

Pericardial mesothelioma should be considered and managed appropriately in non-responders to pericardiocentesis, and in patients who develop constrictive pericarditis late in their clinical course.

SUBMITTER: Butz T 

PROVIDER: S-EPMC2767155 | biostudies-literature | 2009 Sep

REPOSITORIES: biostudies-literature

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Primary malignant pericardial mesothelioma - a rare cause of pericardial effusion and consecutive constrictive pericarditis: a case report.

Butz Thomas T   Faber Lothar L   Langer Christoph C   Körfer Jan J   Lindner Oliver O   Tannapfel Andrea A   Müller Klaus-Michael KM   Meissner Axel A   Plehn Gunnar G   Trappe Hans-Joachim HJ   Horstkotte Dieter D   Piper Cornelia C  

Journal of medical case reports 20090917


<h4>Introduction</h4>Primary malignant pericardial mesothelioma is a very rare pericardial tumor of unknown etiology.<h4>Case presentation</h4>A 61-year-old Caucasian woman was admitted to our hospital complaining of exertional dyspnea due to a large pericardial effusion. Intrapericardial fluid volume declined after repeated pericardiocentesis, but the patient progressively developed a hemodynamically relevant pericardial constriction. Pericardiectomy revealed a pericardial mesothelioma. Subsequ  ...[more]

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