The genetic and molecular regulation of sleep: from fruit flies to humans.
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ABSTRACT:
SUBMITTER: Cirelli C
PROVIDER: S-EPMC2767184 | biostudies-literature | 2009 Aug
REPOSITORIES: biostudies-literature
Publications
The genetic and molecular regulation of sleep: from fruit flies to humans.
Nature reviews. Neuroscience 20090801 8
It has been known for a long time that genetic factors affect sleep quantity and quality. Genetic screens have identified several mutations that affect sleep across species, pointing to an evolutionary conserved regulation of sleep. Moreover, it has also been recognized that sleep affects gene expression. These findings have given valuable insights into the molecular underpinnings of sleep regulation and function that might lead the way to more efficient treatments for sleep disorders. ...[more]
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