Ontology highlight
ABSTRACT:
SUBMITTER: Mendoza VL
PROVIDER: S-EPMC2768138 | biostudies-literature | 2009 Sep-Oct
REPOSITORIES: biostudies-literature
Mass spectrometry reviews 20090901 5
For many years, amino acid-specific covalent labeling has been a valuable tool to study protein structure and protein interactions, especially for systems that are difficult to study by other means. These covalent labeling methods typically map protein structure and interactions by measuring the differential reactivity of amino acid side chains. The reactivity of amino acids in proteins generally depends on the accessibility of the side chain to the reagent, the inherent reactivity of the label ...[more]