Ontology highlight
ABSTRACT:
SUBMITTER: Berberian K
PROVIDER: S-EPMC2768403 | biostudies-literature | 2009 Jan
REPOSITORIES: biostudies-literature
Berberian Khajak K Torres Alexis J AJ Fang Qinghua Q Kisler Kassandra K Lindau Manfred M
The Journal of neuroscience : the official journal of the Society for Neuroscience 20090101 3
The roles of nonmuscle myosin II and cortical actin filaments in chromaffin granule exocytosis were studied by confocal fluorescence microscopy, amperometry, and cell-attached capacitance measurements. Fluorescence imaging indicated decreased mobility of granules near the plasma membrane following inhibition of myosin II function with blebbistatin. Slower fusion pore expansion rates and longer fusion pore lifetimes were observed after inhibition of actin polymerization using cytochalasin D. Ampe ...[more]