Ontology highlight
ABSTRACT:
SUBMITTER: Reider A
PROVIDER: S-EPMC2771086 | biostudies-literature | 2009 Oct
REPOSITORIES: biostudies-literature
The EMBO journal 20090827 20
Internalization of diverse transmembrane cargos from the plasma membrane requires a similarly diverse array of specialized adaptors, yet only a few adaptors have been characterized. We report the identification of the muniscin family of endocytic adaptors that is conserved from yeast to human beings. Solving the structures of yeast muniscin domains confirmed the unique combination of an N-terminal domain homologous to the crescent-shaped membrane-tubulating EFC/F-BAR domains and a C-terminal dom ...[more]