Ontology highlight
ABSTRACT:
SUBMITTER: Aleman C
PROVIDER: S-EPMC2771318 | biostudies-literature | 2009 Oct
REPOSITORIES: biostudies-literature
Alemán Carlos C Jiménez Ana I AI Cativiela Carlos C Nussinov Ruth R Casanovas Jordi J
The Journal of organic chemistry 20091001 20
The intrinsic conformational preferences of the restricted phenylalanine analogue generated by including the alpha and beta carbon atoms into a cyclohexane ring (1-amino-2-phenylcyclohexanecarboxylic acid, c(6)Phe) have been determined using quantum mechanical calculations. Specifically, the conformational profile of the N-acetyl-N'-methylamide derivative of the c(6)Phe stereoisomers exhibiting either a cis or a trans relative orientation between the amino and phenyl substituents has been analyz ...[more]