Clinical correlates and heritability of QT interval duration in blacks: the Jackson Heart Study.

ABSTRACT:

Background

Electrocardiographic QT interval prolongation is a risk factor for sudden cardiac death and drug-induced arrhythmia. The clinical correlates and heritability of QT interval duration in blacks have not been well studied despite their higher risk for sudden cardiac death compared with non-Hispanic whites. We sought to investigate potential correlates of the QT interval and estimate its heritability in the Jackson Heart Study.

Methods and results

The Jackson Heart Study comprises a sample of blacks residing in Jackson, Miss, of whom 5302 individuals with data at the baseline examination were available for study. Jackson Heart Study participants on QT-altering medications, with bundle-branch block, paced rhythm, atrial fibrillation/flutter, or other arrhythmias were e

SUBMITTER: Akylbekova EL 

PROVIDER: S-EPMC2772163 | biostudies-literature | 2009 Aug

REPOSITORIES: biostudies-literature