Ontology highlight
ABSTRACT:
SUBMITTER: Mandelli F
PROVIDER: S-EPMC2773224 | biostudies-literature | 2009 Nov
REPOSITORIES: biostudies-literature
Mandelli Franco F Vignetti Marco M Suciu Stefan S Stasi Roberto R Petti Maria-Concetta MC Meloni Giovanna G Muus Petra P Marmont Filippo F Marie Jean-Pierre JP Labar Boris B Thomas Xavier X Di Raimondo Francesco F Willemze Roel R Liso Vincenzo V Ferrara Felicetto F Baila Liliana L Fazi Paola P Zittoun Robert R Amadori Sergio S de Witte Theo T
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20091013 32
<h4>Purpose</h4>To compare the antitumor efficacy of three different anthracyclines in combination with cytarabine and etoposide in adult patients with newly diagnosed acute myeloid leukemia (AML).<h4>Patients and methods</h4>We randomly assigned 2,157 patients (age range, 15 to 60 years) to receive intensive induction-consolidation chemotherapy containing either daunorubicin, idarubicin, or mitoxantrone. After achieving complete remission (CR), patients were assigned to undergo either allogenei ...[more]