Ontology highlight
ABSTRACT:
SUBMITTER: Clendenon SG
PROVIDER: S-EPMC2773293 | biostudies-literature | 2009 Aug
REPOSITORIES: biostudies-literature
Developmental dynamics : an official publication of the American Association of Anatomists 20090801 8
Cadherin-11/Cdh11 is expressed through early development and strongly during inner ear development (otic placode and vesicle). Here we show that antisense knockdown of Cdh11 during early zebrafish development interferes with otolith formation. Immunofluorescence labeling showed that Cdh11 expression was concentrated on and within the otolith. Cdh11 was faintly detected at the lateral surface (sites of cell-cell contact) of otic epithelial cells and in the cytoplasm. Strongly labeled Cdh11 contai ...[more]