Ontology highlight
ABSTRACT:
SUBMITTER: Alvarez Y
PROVIDER: S-EPMC2773410 | biostudies-literature | 2009 Nov
REPOSITORIES: biostudies-literature
Alvarez Yolanda Y Astudillo Olaya O Jensen Lasse L Reynolds Alison L AL Waghorne Nora N Brazil Derek P DP Cao Yihai Y O'Connor John J JJ Kennedy Breandán N BN
PloS one 20091117 11
Ocular neovascularisation is a pathological hallmark of some forms of debilitating blindness including diabetic retinopathy, age related macular degeneration and retinopathy of prematurity. Current therapies for delaying unwanted ocular angiogenesis include laser surgery or molecular inhibition of the pro-angiogenic factor VEGF. However, targeting of angiogenic pathways other than, or in combination to VEGF, may lead to more effective and safer inhibitors of intraocular angiogenesis. In a small ...[more]