Ontology highlight
ABSTRACT:
SUBMITTER: Reiter L
PROVIDER: S-EPMC2773710 | biostudies-literature | 2009 Nov
REPOSITORIES: biostudies-literature
Reiter Lukas L Claassen Manfred M Schrimpf Sabine P SP Jovanovic Marko M Schmidt Alexander A Buhmann Joachim M JM Hengartner Michael O MO Aebersold Ruedi R
Molecular & cellular proteomics : MCP 20090716 11
Comprehensive characterization of a proteome is a fundamental goal in proteomics. To achieve saturation coverage of a proteome or specific subproteome via tandem mass spectrometric identification of tryptic protein sample digests, proteomics data sets are growing dramatically in size and heterogeneity. The trend toward very large integrated data sets poses so far unsolved challenges to control the uncertainty of protein identifications going beyond well established confidence measures for peptid ...[more]