Ontology highlight
ABSTRACT:
SUBMITTER: Huang Z
PROVIDER: S-EPMC2773798 | biostudies-literature | 2009
REPOSITORIES: biostudies-literature
Huang Zhaohua Z Jaafari Mahmoud Reza MR Szoka Francis C FC
Angewandte Chemie (International ed. in English) 20090101 23
Extreme makeover of cholesterol: Cholesterol exchange is a major reason for the instability of liposomes in blood. The formation of a covalent hybrid between cholesterol and glycerophosphocholine preserves the bilayer-stabilizing effect of free cholesterol but prevents its transfer from the bilayer. Thus, disterolphospholipids (e.g. 1) are valuable new components for liposome formulation. ...[more]