Cancer pharmacoethnicity: ethnic differences in susceptibility to the effects of chemotherapy.
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ABSTRACT:
SUBMITTER: O'Donnell PH
PROVIDER: S-EPMC2774468 | biostudies-literature | 2009 Aug
REPOSITORIES: biostudies-literature
Publications
Cancer pharmacoethnicity: ethnic differences in susceptibility to the effects of chemotherapy.
O'Donnell Peter H PH Dolan M Eileen ME
Clinical cancer research : an official journal of the American Association for Cancer Research 20090721 15
A long-term goal of pharmacogenomics research is the design of individualized therapy based on the genomic sequence of the patient, in order to maximize response and minimize adverse drug reactions. Pharmacoethnicity, or ethnic diversity in drug response or toxicity, is becoming increasingly recognized as an important factor accounting for interindividual variation in anticancer drug responsiveness. Although pharmacoethnicity is determined by genetic and nongenetic factors, there is rapidly accu ...[more]
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