Ontology highlight
ABSTRACT:
SUBMITTER: Anderson S
PROVIDER: S-EPMC2774740 | biostudies-literature | 2005 Jun
REPOSITORIES: biostudies-literature
Anderson Spencer S Dragnea Vladimira V Masuda Shinji S Ybe Joel J Moffat Keith K Bauer Carl C
Biochemistry 20050601 22
The flavin-binding BLUF domain of AppA represents a new class of blue light photoreceptors that are present in a number of bacterial and algal species. The dark state X-ray structure of this domain was determined at 2.3 A resolution. The domain demonstrates a new function for the common ferredoxin-like fold; two long alpha-helices flank the flavin, which is bound with its isoalloxazine ring perpendicular to a five-stranded beta-sheet. The hydrogen bond network and the overall protein topology of ...[more]