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SimCT: a generic tool to visualize ontology-based relationships for biological objects.


ABSTRACT: UNLABELLED: We present a web-based service, SimCT, which allows to graphically display the relationships between biological objects (e.g. genes or proteins) based on their annotations to a biomedical ontology. The result is presented as a tree of these objects, which can be viewed and explored through a specific java applet designed to highlight relevant features. Unlike the numerous tools that search for overrepresented terms, SimCT draws a simplified representation of biological terms present in the set of objects, and can be applied to any ontology for which annotation data is available. Being web-based, it does not require prior installation, and provides an intuitive, easy-to-use service. AVAILABILITY: http://tagc.univ-mrs.fr/SimCT. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.

SUBMITTER: Herrmann C 

PROVIDER: S-EPMC2778334 | biostudies-literature | 2009 Dec

REPOSITORIES: biostudies-literature

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SimCT: a generic tool to visualize ontology-based relationships for biological objects.

Herrmann Carl C   Bérard Sèverine S   Tichit Laurent L  

Bioinformatics (Oxford, England) 20090923 23


<h4>Unlabelled</h4>We present a web-based service, SimCT, which allows to graphically display the relationships between biological objects (e.g. genes or proteins) based on their annotations to a biomedical ontology. The result is presented as a tree of these objects, which can be viewed and explored through a specific java applet designed to highlight relevant features. Unlike the numerous tools that search for overrepresented terms, SimCT draws a simplified representation of biological terms p  ...[more]

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