Ontology highlight
ABSTRACT:
SUBMITTER: Sehl ME
PROVIDER: S-EPMC2778342 | biostudies-literature | 2009 Mar
REPOSITORIES: biostudies-literature
Sehl Mary E ME Langer Lucy R LR Papp Jeanette C JC Kwan Lorna L Seldon Joyce L JL Arellano Geovanni G Reiss Jean J Reed Elaine F EF Dandekar Sugandha S Korin Yael Y Sinsheimer Janet S JS Zhang Zuo-Feng ZF Ganz Patricia A PA
Clinical cancer research : an official journal of the American Association for Cancer Research 20090310 6
<h4>Purpose</h4>DNA damage recognition and repair play a major role in risk for breast cancer. We investigated 104 single nucleotide polymorphisms (SNP) in 17 genes whose protein products are involved in double-stranded break repair (DSBR).<h4>Experimental design</h4>We used a case-control design. Both the case individuals affected with breast cancer or with both breast and ovarian cancers and the controls had similar familial risk of breast cancer and were participants in a high-risk cancer reg ...[more]