Ontology highlight
ABSTRACT:
SUBMITTER: Faraggi E
PROVIDER: S-EPMC2778607 | biostudies-literature | 2009 Nov
REPOSITORIES: biostudies-literature
Structure (London, England : 1993) 20091101 11
Local structures predicted from protein sequences are used extensively in every aspect of modeling and prediction of protein structure and function. For more than 50 years, they have been predicted at a low-resolution coarse-grained level (e.g., three-state secondary structure). Here, we combine a two-state classifier with real-value predictor to predict local structure in continuous representation by backbone torsion angles. The accuracy of the angles predicted by this approach is close to that ...[more]