Ontology highlight
ABSTRACT:
SUBMITTER: Evjenth R
PROVIDER: S-EPMC2781511 | biostudies-literature | 2009 Nov
REPOSITORIES: biostudies-literature
Evjenth Rune R Hole Kristine K Karlsen Odd A OA Ziegler Mathias M Arnesen Thomas T Lillehaug Johan R JR
The Journal of biological chemistry 20090910 45
Protein acetylation is a widespread modification that is mediated by site-selective acetyltransferases. KATs (lysine N(epsilon)-acetyltransferases), modify the side chain of specific lysines on histones and other proteins, a central process in regulating gene expression. N(alpha)-terminal acetylation occurs on the ribosome where the alpha amino group of nascent polypeptides is acetylated by NATs (N-terminal acetyltransferase). In yeast, three different NAT complexes were identified NatA, NatB, a ...[more]